Selected Publications
Nizami HL, Minor KE, Chiao YA, Light CM, Lee CF*. Sexually dimorphic effects of SARM1 deletion on cardiac NAD+ metabolism and function. American journal of physiology. Heart and circulatory physiology, 2022 Oct 1;323(4):H774-H781. doi: 10.1152/ajpheart.00370.2022. Epub 2022 Sep 2. PubMed PMID: 36053750; PubMed Central PMCID: PMC9529255.
Chakraborty AD, Minor KE, Nizami HL, Chiao YA and Lee CF*. Harnessing NAD+ metabolism as therapy for cardiometabolic diseases. Current heart failure reports, 2022 Aug;19(4):157-169. doi: 10.1007/s11897-022-00550-5. Epub 2022 May 13. PMID: 35556214; PMCID: PMC9339518.
Chiao YA, Chakraborty AD, Light CM, Tian R, Sadoshima J, Shi X, Gu H, Lee CF*. NAD+ redox imbalance in the heart exacerbates diabetic cardiomyopathy. Circulation. Heart failure, 2021 Aug 10;14(8):e008170. PMID: 34374300 PMCID: PMC8373812.
Lee CF, Caudal A, Abell L, Nagana Gowda GA, Tian R. Targeting NAD+ metabolism as interventions for mitochondrial disease in a Leigh Syndrome Mouse Model. Scientific reports, 2019 Feb 28;9(1):3073. PMID: 30816177 PMCID: PMC6395802.
Schweppe DK, Chavez JD, Lee CF, Caudal A, Kruse SE, Stuppard R, Marcinek DJ, Shadel GS, Tian R, Bruce JE. Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America, 2017;114(7):1732-1737. PMID: 28130547 PMCID: PMC5321032.
Lee CF, Chavez JD, Garcia-Menendez L, Choi Y, Roe ND, Chiao YA, Edgar JS, Goo Y, Goodlett D, Bruce JE, Tian R. Normalization of NAD+ redox balance as a therapy for heart failure. Circulation, 2016;134:883-94. PMID: 27489254, PMCID: 5193133.
Lee CF, Tian R. Mitochondrion as a target of heart failure therapy: the role of protein lysine acetylation. Circulation Journal, 2015;79(9):1863-70. PMID: 26248514.
Karamanlidis G, Lee CF, Garcia-Menendez L, Kolwicz SC, Jr., Suthammarak W, Gong G, Sedensky MM, Morgan PG, Wang W, and Tian R. Mitochondrial complex I deficiency increases protein acetylation and accelerates heart failure. Cell Metabolism, 2013;18(2):239-50. PMID: 23931755, PMCID: PMC3779647.
*Corresponding author